Product Name:Berberine Hydrochloride
Used Part: Bark
Appearance: Yellow Crystalline Powder
Specification: 97% 98% Berberine Hydrochloride
Detection Method: HPLC & UV
Extract Source
Berberine hydrochloride is an isoquinoline alkaloid that exists in many plants from 4 families and 10 genera including the Berberidaceae family.
Berberine hydrochloride, also known as berberine hydrochloride, has long been used clinically as a heat-clearing, detoxifying and antibacterial drug. It is often used to treat diseases such as bacillary dysentery, acute gastroenteritis, chronic cholecystitis, conjunctivitis, and suppurative otitis media, all of which have significant effects.
Berberine can precipitate yellow needle-like crystals from ether. Berberine is a quaternary ammonium alkaloid, and the solubility of its salts in water is relatively small, for example, the hydrochloride is 1:500 and the sulfate is 1:30.
Certificates of Analysis
| Product Name: |
Phellodendron Amurense Extract |
Latin Name: |
Cortex Phellodendri Chinensis |
| Part used: |
Bark |
Country of origin |
China |
| |
| Appearance |
Fine powder |
Organoleptic |
| Color |
Yellow Crystal Powder |
Visual |
| Odour & Taste |
Characteristic |
Organoleptic |
| Berberine Hydrochloride |
NLT 97.0% |
HPLC |
| Sieve Analysis |
90% through 80 mesh |
USP39 <786> |
| Loss on drying |
≤ 5.0% |
Eur.Ph.9.0 [2.5.12] |
| Total Ash |
≤ 5.0% |
Eur.Ph.9.0 [2.4.16] |
| Lead (Pb) |
≤ 3.0 mg/kg |
Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) |
≤ 1.0 mg/kg |
Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium(Cd) |
≤ 1.0 mg/kg |
Eur.Ph.9.0<2.2.58>ICP-MS |
| Mercury(Hg) |
≤ 0.1 mg/kg -Reg.EC629/2008 |
Eur.Ph.9.0<2.2.58>ICP-MS |
| Heavy metal |
≤ 10.0 mg/kg |
Eur.Ph.9.0<2.4.8> |
| Solvents Residue |
Conform Eur.ph. 9.0 <5,4 > and EC European Directive 2009/32 |
Eur.Ph.9.0<2.4.24> |
| Pesticides Residues |
Conform Regulations(EC) No.396/2005 including annexes and successive updates Reg.2008/839/CE |
Gas Chromatography |
| Aerobic bacteria(TAMC) |
≤1000 cfu/g |
USP39 <61> |
| Yeast/Moulds(TAMC) |
≤100 cfu/g |
USP39 <61> |
| Escherichia coli: |
Absent in 1g |
USP39 <62> |
| Salmonella spp: |
Absent in 25g |
USP39 <62> |
| Staphylococcus aureus: |
Absent in 1g |
|
| Listeria Monocytogenens |
Absent in 25g |
|
| Aflatoxins B1 |
≤ 5 ppb -Reg.EC 1881/2006 |
USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 |
≤ 10 ppb -Reg.EC 1881/2006 |
USP39 <62> |
Efficacy and function
1. Berberine hydrochloride has the effects of clearing away heat and promoting dampness, purging fire and detoxifying.
2. Berberine hydrochloride has anti-inflammatory, antibacterial, antiviral and antiprotozoal effects, and has a significant inhibitory effect on influenza viruses.
3. Berberine hydrochloride has the effect of relaxing vascular smooth muscle and anti-diarrhea.
4. Berberine hydrochloride has the effects of anti-arrhythmia, lowering blood pressure, and regulating blood concentration.
5. Berberine hydrochloride has a choleretic effect and can increase bile secretion.
6. Berberine hydrochloride has anti-cerebral ischemia effect, can reduce acute ischemic stroke, reduce the expression level of MDA, and improve the degree of neurological deficit.
Application
1.Used in the field of pharmaceutical products to helps in the treatment of various diseases
2.Used in the field of health care products to help the human body fight viruses
3.Used in the field of cosmetics, usually added to capsules or tablets for the treatment of cardiovascular and cerebrovascular diseases.
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