| Customization: | Available |
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| Certification: | ISO, FDA |
| Assay Method: | HPLC |
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Efficacy and function
1. Anti alcohol effect
The extract of Fructus aurantii fructus can inhibit the absorption of ethanol by digestive tract, and can effectively slow down and hinder the speed and concentration of ethanol entering the body, thus reducing the effect of ethanol on liver and other organs official brings damage. The change of the activity of alcohol dehydrogenase will affect the concentration of alcohol in blood. The decrease of the activity of this enzyme can improve the bioavailability of ethanol, and further aggravate the harm of ethanol to brain, liver and other organs. The water extract of Fructus ponantii orange chess can significantly improve the activity of alcohol dehydrogenase and has the effect of antialcohol. Accumulation of pieces can reverse the ethanol the decreased activity of ethanol dehydrogenase keeps the balance between the production and accumulation of acetaldehyde, the intermediate product of ethanol oxidation.
2. Liver protection effect
The extract can block the occurrence and development of hepatic fibrosis and promote the repair and regeneration of hepatic cells. Significantly inhibited the elevation of ALT and AST induced by ethanol and LPS; It can protect liver lipid peroxidation caused by ethanol and delay and prevent fatty liver formation caused by ethanol. It has growth-promoting activity on liver cells and can significantly improve liver cell survival and proliferation rate.
3. Anti-mutagenic effect
A compound extracted and isolated from Fructus aurantii, showing excellent anti-mutagenic activity in the Emme assay and used in cancer prevention.
4. Anti-tumor effect
The water extract of Fructus aurantii had inhibitory effect on the growth of human hepatocellular carcinoma Bel-7402 cells cultured in vitro. The mice inoculated with mouse hepatocellular carcinoma strain H22 were given intragastric administration of the water extract of Fructus aurantii aurantii had a significant inhibitory effect on tumor.
5. Anti-aging effect
The extract of trifoliate aurantium could improve the learning and memory ability of subacute aging mice induced by D-galactose and had the effect of delaying aging. This effect is caused by increasing the activity of antioxidant enzymes in the body, reducing the production of lipid peroxidation and improving the antioxidant capacity of the body.
6. Enhance physical function
The water extract of Fructus aurantii aurantii could significantly improve the cold resistance and heat resistance of mice and prolong the swimming and pole climbing time of mice. Conclusion The water extract of Fructus aurantii has the effect of enhancing the comprehensive physical strength of mice.
7. Other functions
Fructus aurantium had obvious inhibitory effect on stress gastric ulcer. It has certain inhibitory effect on central nervous system. It can inhibit sweet taste. It can inhibit the release of histamine. It has sedative, antispasmodic and analgesic effects. It has a significant diuretic effect.
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