| Customization: | Available |
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| Certification: | ISO, FDA, Hahal, Food Manufacturing License, Business Licens |
| Assay Method: | HPLC, UV |
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| Description:
Myricetin (3,3′,4′,5,5′,7-Hexahydroxyflavone) is a cell-permeable flavanoid used in inflammatory, diabetes, and cancer studies. Myricetin has been shown to act as a non-ATP competitive inhibitor of MEK-1. Myricetin is also an ATP-competitive inhibitor of several other factors including casein kinases I & II, Insuli-n Receptor, Myosin LC kinase, PKA (Protein Kinases A), PKC (Protein Kinases C), PI 3-kinase and Pim-1 (PIM-1). Myricetin is an inhibitor of CYP2C9, CYP3A4, Maltase-glucoamylase and MYLK. Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity. Application: |
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