Natural Peppermint Extract 10: 1-100: 1 Mentha Haplocalyx Briq.

• Certification: ISO, FDA, SGS, Halal, Sc&Bl
• Assay Method: HPLC, UV, Tlc
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Brownish Yellow Powder
• Extract Source: Fruit
• Payment: T/T in Advance
• Shelf Life: 24 Months
• Delivery Time: 3-5 Working Days
• Free Sample: Available
• Transport Package: 25kg/Cardboard Drum I. D. 42cm X H. 52cm
• Specification: 10: 1-100: 1
• Trademark: Shanghai, China
• Origin: China
• HS Code: 13021990
• Production Capacity: 20 Ton/Month

Product Description

Product Profile
Peppermint extract is the dried whole plant extract of Mentha hap localyxBriq., a plant belonging to the genus Mentha of the Lamiaceae family. The volatile oil is the main active ingredient and is customarily called peppermint oil or peppermint crude oil; a large amount of colorless substances precipitated at low temperatures are called menthol. ; The oil from which part of the menthol is separated is called peppermint oil; the refined product of peppermint oil is called peppermint white oil. All these commodities have different quality requirements in the international market. The main components of peppermint oil are L-menthol (Mentho1) and flavonoids. It has anti-tumor, anti-inflammatory and analgesic effects. It also has important regulatory functions on the central nervous system, digestive system, and antibacterial and anti-inflammatory systems. It is widely used in food and pharmaceutical industry.

Mint is the whole plant of the Lamiaceae plant MenthahaplocalyxBriq. Perennial herb, fragrant, 30-70 cm tall. The rhizomes penetrate deeply into the soil and are easily broken. The stem is upright, quadrangular, with retro villous hairs and glandular points. The single leaves are opposite, the petiole is 2~12 mm long, densely covered with white pubescence, the leaves are oval, the apex is pointed or acuminate, the base is wedge-shaped, the edge has finely serrated edges, and dense cilium. The surface is white pubescent, the back is pubescent and glandular; the inflorescences are axillary; the bracts are 1, linear-lanceolate; the calyx is bell-shaped, 5-lobed, with 5 obvious longitudinal veins; the corolla is 2-lipped, Light red; stamens 4, anthers yellow; ovary 4-parted, stigma 2. Nutlets 1 mm, hidden in contracted calyx. The flowering period is from August to October, and the fruiting period is from September to November. Born in mountain roadsides, streams and other places. Produced in Xifeng, Jianping, Lingyuan, Qingyuan, Shenyang, Anshan, Huanren, Zhuanghe, Pulandian, Jinzhou, Dalian and other cities and counties.

Function
1. Effect on digestive system
1.1. Relieve spasms and strengthen stomach
Peppermint ethanol extract has a significant inhibitory effect on the contraction of isolated ileum of guinea pigs induced by acetylcholine or histamine. Peppermint oil has an anti-acetylcholine (antispasmodic) effect on isolated mouse intestines, and can increase intestinal peristalsis in vivo, but has no effect on promoting intestinal propulsive peristalsis, and sometimes even inhibits it. Menthol and menthone have inhibitory effects on isolated rabbit intestines, and the latter is twice as powerful as the former. Peppermint oil also has stomachic properties, possibly secondary to its stimulation of the senses of smell and taste. The pandan oil hydrocarbon in peppermint oil has a preventive and therapeutic effect on experimental gastric ulcer in rats caused by phenylbutadione.

1.2. Choleretic effect
Rats 1.5 hours after bile drainage were given peppermint acetone dry extract and 50% methanol extract respectively. The amount of bile secretion increased significantly, reaching a peak at 30 minutes and increasing by about 3.9 times. Menthol and menthone showed strong choleretic effects when administered orally to rats. Rats were given menthol and menthone by gavage respectively. The former increased bile excretion by 4 times after 3 to 4 hours, and then the effect weakened; the latter had similar effects and was longer-lasting, with bile excretion increasing by 50% to 100% after 5 hours. The choleretic effect of menthol is greater than that of acetylmenthol, and the maximum secretion volumes are 0.71mL and 0.54mL respectively, which shows that the alcoholic hydroxyl group plays an important role in producing the choleretic effect.

1.3. Liver protection
Subcutaneous injection of peppermint injection can significantly reduce serum alanine aminotransferase activity in rats with liver damage caused by CCl4, but does not return to normal. The liver cell swelling and degeneration were lighter than those in the control group, but the necrotic lesions were more serious than those in the control group.

2. Anti-pathogenic bacteria
2.1. Anti-virus
100% peppermint aqueous extract 10 mg/mL can inhibit 10 to 100 TCID50 (half of the tissue culture infection dose) herpes simplex virus infection in primary suckling rabbit kidney epithelial cell culture. Increasing the infection dose has no inhibitory effect. If the concentration of the water extract is increased to 100mg/mL, it will have a toxic effect on cells. 5% peppermint water extract also has an inhibitory effect on orphan viruses. If taken at the same time during infection, it can also delay the appearance of lesions. The water extract of mint, a plant belonging to the same genus, has inhibitory effects on herpes simplex virus, vaccinia virus, Semliki forest virus and mumps virus.

2.2. Antibacterial
Peppermint water extract is effective against Staphylococcus aureus, Staphylococcus albus, Type A and Type B Streptococcus, Catarrhalis, Enteritidis, Pneumoniae, Shigella flexneri, Bacillus anthracis, Diphtheria, Typhi, and Pseudomonas aeruginosa. , Escherichia coli, Proteus, human Mycobacterium tuberculosis, etc. all have inhibitory effects. In addition to its strong antibacterial effect on a variety of bacteria, mint also has a strong inhibitory effect on a variety of fungi such as Candida albicans, Microsporum, Penicillium, Aspergillus, Corychosporium, and Conchosporium.

2.3. Deworming
Peppermint oil repels roundworms in dogs and cats. In addition, D-8-acetoxyallodihydrocarvone is an effective ingredient in wild mint that repels insects. It has a good repellent effect on biting insects (such as mosquitoes, flies, etc.), and has low toxicity and is not harmful to human skin. Less irritating.

3. Anti-early pregnancy
The water-soluble part of peppermint and peppermint oil have direct uterine stimulation and anti-fertility effects.

4. Effect on respiratory system
Inhalation of 81mg/kg of menthol vapor in urethane-anesthetized rabbits can increase the secretion of respiratory mucus and reduce the specific gravity of secretions; inhalation of 243mg/kg can reduce the amount of mucus discharge, which may be a direct effect on respiratory mucus cells. Menthol can reduce the foaming of blood and saponins. When used for bronchitis, it can reduce foamy sputum in the respiratory tract and increase the effective ventilation tract. When used for rhinitis and laryngitis, it may be because menthol can promote secretion and dilute viscous liquid, thus showing obvious relief effect. It has also been reported that menthol has a good antitussive effect on guinea pigs and humans.

5. Effect on the central nervous system
Taking a small amount of peppermint orally has a diaphoretic and antipyretic effect, which mainly stimulates the central nervous system, dilates skin capillaries, and promotes sweat gland secretion to increase heat dissipation. The essential oils of peppermint and mint from the same genus can prolong the sleep time induced by sodium pentobarbital (50mg/kg). Both have inhibitory effects on the central system, and the latter can prolong the central inhibition time in mice more than the former. In the measurement of spontaneous activity, peppermint essential oil is more effective in suppressing the central system than peppermint essential oil, but both have no effect on the conditioned reflex of rats. Different doses of the two can also lower the body temperature of mice and rats. When 1g/kg of peppermint extract is injected subcutaneously, the inhibition rate of the acetic acid writhing reaction in mice is 30% to 60%, and its active ingredient is menthol. Menthone also has a strong analgesic effect. The inhibition rate of 100mg/kg intragastric administration on the acetic acid writhing reaction in mice was 41.3%.

6. Anti-inflammatory effect
Intraperitoneal injection of 250 mg/kg peppermint extract has an inhibitory rate of 60% to 100% on carrageenan foot swelling in rats. The main active ingredient is menthol. Various components extracted from mint leaves with dihydroxy-1,2-dihydronaphthalene dicarboxylic acid as the core have anti-inflammatory effects, among which 1-(3,4-dihydroxyphenyl)-3[2- (3,4-dihydroxyphenyl)-1-carboxy]ethoxycarbonyl-6,7-dihydroxy-1,2-dihydronaphthalene-2-carboxylic acid has obvious anti-inflammatory effects, and its anti-3α-hydroxy The IC50 of steroid dehydrogenase is 28.0 μg/mL, while the IC50 of aspirin against this enzyme is 1150.0 μg/mL, and the IC50 of the other eight extracts is 6.1 to 63.7 μg/mL.

7.Other functions
Peppermint oil also has a paralyzing effect on isolated frog hearts, and vascular perfusion has a vasodilatory effect. Menthone can excite rabbits and dogs, lower blood pressure, and has an inhibitory effect on isolated frog hearts. Peppermint aqueous extract has an inhibitory effect on concanavalin A (ConA)-induced histamine release. Peppermint extract has an inhibitory effect on calcium channel blocker receptors and adenylyl cyclase, and has a significant protective effect on skin damage caused by radiation.

Certificates of Analysis
 

Product Name:	Peppermint Extract		Latin name		Mentha haplocalyx Briq
Part used:	Fruit		Country of origin		China
Item		Specification		Result
Assay		10:1		TLC
Physical & Chemical
Appearance		Brownish Yellow Powder		Conforms
Odor & Taste		Characteristic		Characteristic
Particle Size		90% through 80 mesh		Conforms
Loss on Drying		≤5.0%		1.32%
Ash		≤5.0%		2.11%
Heavy metals
As		≤2ppm		Conforms
Lead (Pb)		≤2ppm		Conforms
Cadmium(Cd)		≤1ppm		Conforms
Microbiological Test
Total Plate Count		NMT 1000cfu/g		Conforms
Total Yeast & Mold		NMT 100cfu/g		Conforms
E.Coli		Negative		Negative
Salmonella		Negative		Negative
Pesticide Residue		Negative		Negative