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| Assay Method: | HPLC, UV |
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| Description: Coleus forskohlii is an erect, branched, densely hairy, annual or perennial herb that normally grows about 45 - 60 cm tall. The plant is found growing in open dry slopes, dry stony hills, barren hills, grasslands, dry deciduous forests and chir pine forest. It flourishes in well-drained soil in sun or partial shade. Roots are typically golden brown, thick, fibrous and radially spreading. Roots are tuberous, fasciculated, 20 cm long and 0.5 to 2.5 cm in diameter, conical fusiform, straight, orange-red within and strongly aromatic. Stems are erect or ascending, unbranched or with few branches, 20-30 (-60) cm, quadrangular, somewhat sturdy, with long multicellular glandular hairs and short glandular hairs, and with or without red oil globules. Six other species of Coleus have been explored but only C. forskohlii consists of forskolin. Indian borage (C. amboinicus) is used traditionally within Ayurvedic and Unam Tibb herbal medicine to help reduce inflammation and is prescribed for bronchitis and asthma. Leaves Leaves are ovate to oblong, blunt, rounded-toothed and short-stalked. They are arranged in opposite pairs perpendicular to each other, along a 1-3 ft. tall stem. They are 7.5 to 12.5 cm in length and 3 to 5 cm in width, usually pubescent, narrowed into petioles. The plant is strongly aromatic and the leaves have distinctive camphor like scent. Both root and leaves are harvested in autumn. Flowers Inflorescence is raceme, 15 - 30 cm long. Flowers are stout, up to 2 to 2.5 cm in size, tube bent abruptly downward, longer than the sepal cup. Flowers are 2-lipped, the upper lip is short, broadly ovate, turned back, 3-lobed, the lower much longer, boat-shaped, pointed. Sepal cup is hairy, bell-shaped, with lance shaped, prickly-tipped sepals. Bracts are broadly ovate, pointed, overlapping in bud, soon falling. The ovary is four parted and stigma is two lobed and the flower is cross-pollinated by wind or insects. Flowering normally takes place from August till October. Fruits Fertile flowers are followed by dry, one-seeded, globose, slightly flattened laterally nut lets that are 1.4 mm long and 1.4 mm wide, included in persistent calyx. They are shiny, dark brown colored. Health Benefits: 1. Circulatory remedy An important heart and circulatory tonic, coleus is used to treat congestive heart failure and poor coronary blood flow. It also improves circulation of blood to the brain. 2. Respiratory problems Its antispasmodic action makes coleus valuable for respiratory complaints, including asthma and bronchitis. 3. Cures Glaucoma Glaucoma is characterized by elevated intraocular pressure (IOP). It is a condition in which the pressure in the eye is too high, due to an imbalance between the formation of aqueous humor in the eye and its absorption in or drainage out of the eye. Eventually, as the pressure builds up, the blood vessels nourishing the optic nerve are constricted, resulting in irreversible damage to the nerve and impaired vision culminating in blindness, if left untreated. Several animal and human research have demonstrated the ability of forskolin to lower IOP, possibly via cAMP activation and a reduction in aqueous flow. 4. Anti-Hypertensive Benefit Recent research confirmed that coleus consists of a powerful compound called forskolin that may have muscle relaxant properties and can dilate blood vessels thus has a capability to lower blood pressure (anti-hypertensive property). With dilated blood vessels the heart works less to pump blood throughout the body. Coleus can provide health benefit for patients suffering from cardiomyopathy. 5. Beneficial for Hypo-thyrodism Forskolin found in coleus has been found to regulate various enzymes and hormones in human body. It may be used to control and cure thyroid gland malfunctioning, particularly when the gland is under functioning (hypothyroidism). 6. Promote weight-loss Active chemical found in Coleus herb is forskolin has been found to promote weight loss in patients who are considered obese. Research has shown that forskolin in coleus can boost the production of enzyme called adenylate cyclase and as a result likewise boost another enzyme called cAMP. This dropping reaction of enzymes forces the fat cells to burn and release their stored energy. 7. Asthma and Allergic Reactions By stabilizing body cells responsible for the release of histamines, which trigger allergies, and relaxing smooth tissues of the muscle, Coleus Forskohlii is important in the treatment of allergic respiratory conditions such as asthma. 8. Boosting Sexual Libido Coleus Forskohlii is among the various nutritional supplements recommended for boosting the male hormone testosteron-e, responsible for sexual vigor. Additionally, by strengthening the heartbeat while lowering blood pressure, sexual performance has been shown to improve using extracts from the herb. 9. Treatment of Psoriasis Psoriasis is a skin condition characterized by dry, rough, dead skin on the scalp, knees, groin or lower back. The exact cause is not exactly known but scientists suspect a weak immune system could be among the causes. Because of its ability to boost the body's immune system, Coleus Forskohlii is among the various remedies prescribed for the skin condition. 10. Relief from Irritable Bowel Syndrome (IBS) It is a disorder of the intestines with symptoms such as irregular bowel movements, abdominal pains, cramps and bloating. Coleus Forskohlii offer relief against this condition by acting on the inflammation of the intestines which aids in the process of digestion thus providing relief against IBS. 11. Boosting Metabolism It is closely related to providing relief against IBS, Coleus Forskohlii aids in the digestive process by boosting the production of stomach acids thus aiding in digestion thus improving our metabolism. rial infection. |
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