99% Phenethyl Caffeate Powder Pure Powder CAS 104594-70-9 Phenethyl Caffeate Cosmetic Grade Caffeic Acid Phenethyl Ester Powder

• Certification: ISO, FDA
• Assay Method: HPLC, UV, Tlc
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: /
• Payment: T/T in Advance
• Shelf Life: 24 Months
• Delivery Time: 3-5 Working Days
• Free Sample: Available
• Transport Package: 25kg/Cardboard Drum I. D. 42cm X H. 52cm
• Specification: 99%
• Trademark: Shanghai, China
• Origin: China
• HS Code: 13021990
• Production Capacity: 20 Ton/Month

Product Description

Product Profile
Caffeic acid phenethyl ester, referred to as CPAE, is one of the main active components of propolis and is effective against herpes viruses. Other viruses inhibited by components in propolis include adenovirus and influenza virus.

CAPE, quercetin, isoprenyl esters, rhamnetin, glaucomin, glycosides, polysaccharides and other substances in propolis have anti-cancer activity, can inhibit the proliferation of tumor cells, and have a certain poisoning effect on cancer cells. , and CAPE has specific killing power against tumor cells.

Jeng et al. believe that CAPE is involved in inducing natural cell death and has a cytotoxic effect on malignant diseased tissues. CAPE can improve the effects of tumor factors (12-0-tetradecanoylfurbolol-13-ethyl) at very small concentrations. acid ester)-induced inflammatory reaction.

The structure of caffeic acid phenethyl ester contains an 0-dihydroxy (catechol) phenyl structure, which is a common structure for scavenging free radicals. It also has two ortho-position phenolic hydroxyl groups, which makes the electron density on the benzene ring high and extremely Easy to auto-oxidize and develop color. Bors et al. reported that the 0-dihydroxybenzene ring structure plays an important role in the antioxidant effect of flavonoids.

The chemical composition of propolis in different regions is different, so the CAPE content is also different. Studies have shown that the CAPE content in propolis produced in China is relatively high, reaching 15 ~ 25mg/g, while the propolis produced in Brazil does not contain CAPE. The laboratory uses caffeic acid and β-bromoethylbenzene as raw materials and potassium phosphate as a catalyst to synthesize caffeic acid phenethyl ester with a yield of up to 60%.

Application
1. Caffeic acid is  known as an antioxidant in vitro and also in vivo. 
2. Caffeic acid phenethyl ester also shows immunomodulatory and anti-inflammatory activity.
3. Caffeic acid phenethyl ester outperformed the other antioxidants.

Certificates of Analysis
 

Product Name:	Phenethyl Caffeate		CAS No.:		104594-70-9
Chemical formula:	C9H8O4		Country of origin		China
Item		Specification		Result
Aaasy		99%		TLC
Physical & Chemical
Appearance		Off-white powder		Conforms
Odor & Taste		Characteristic		Characteristic
Particle Size		90% through 80 mesh		Conforms
Loss on Drying		≤5.0%		1.60%
Ash		≤5.0%		2.13%
Heavy metals
As		≤2ppm		Conforms
Lead (Pb)		≤2ppm		Conforms
Cadmium(Cd)		≤1ppm		Conforms
Microbiological Test
Total Plate Count		NMT 10000cfu/g		Conforms
Total Yeast & Mold		NMT 1000cfu/g		Conforms
E.Coli		Negative		Negative
Salmonella		Negative		Negative
Pesticide Residue		Negative		Negative