Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects as well as κ-opioid and μ-opioid receptor agonism.Matrine possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities.
Matrine is a component of the traditional Chinese medical herb Sophora flavescens Ait. Matrine and the related compound oxymatrine have an antifeedant effect against formosan subterranean termite.
| Product name |
Matrine |
| Botanical resource |
Sophora flavescens Ait |
| Apperance |
White fine power |
| Specification |
99% |
| Test method |
HPLC |
| Shelf time |
2 years,keep away sunlight, keep dry |
Certificate of Analysis
| Analysis |
Specification |
Results |
| Assay(Sophocarpidine) |
≥98.0% |
98.05% |
| Physical & Chemical Control |
|
| Identification |
Positive |
Complies |
| Appearance |
White Powder |
Complies |
| Odor |
Characteristic |
Complies |
| Mesh Size |
80 mesh |
Complies |
| Loss On Drying |
≤5.0% |
2.27% |
| Methanol |
≤5.0% |
0.024% |
| Ethanol |
≤5.0% |
0.150% |
| Residue on Ignition |
≤3.0% |
1.05% |
| Heavy Metal Testing |
|
|
| Heavy Metals |
<20ppm |
Complies |
| As |
<2ppm |
Complies |
| LEAD(Pb) |
< 0.5PPM |
0.22 ppm |
| MERCURY(Hg) |
Not dectect |
Complies |
| CADMIUM |
< 1 PPM |
0.25 ppm |
| COPPER |
< 1 PPM |
0.32 ppm |
| ARSENIC |
< 1 PPM |
0.11 ppm |
| Microbiological |
|
|
| Total Plate Count |
<1000/gMax |
Complies |
| Staphylococcus Aurenus |
Not Detected |
Negative |
| Pseudomonas |
Not Detected |
Negative |
| Yeast & Mold |
<100/gMax |
Complies |
| Salmonella |
Negative |
Negative |
| E. Coli |
Negative |
Negative |
Function:
1.It has obvious inhibition on heart, which can slow the heart rate, weaken the myocardial contractility, and reduce cardiac output;
2. Having anti-arrhythmia effects;
3. It has rapid and long-lasting effect on aconitine-induced arrhythmias. And it also has anti-hypertensive effect;
4. Inhibiting on Mycobacterium tuberculosis, Shigella, Staphylococcus aureus, Escherichia coli, and a variety of skin fungus;
5. Inducing diuresis, reducing inflammation, preventing allergies, making people calm down, relieving asthma, eliminating phlegm, elevating white blood cell count, and fighting cancer.
Application
1. Matrine is widely used in pesticide in recent years;
2. Matrine has function of relieving internal heat;
3. Matrine has effect on anti-bacteria, anti-inflammatory;
4. Matrine is used for suppressing sarcoma S180, anti-tumors;
5) Matrine can cure tonsillitis, mastitis, smooth the asthma etc.when taken orally;
6. Matrine can improve the leucocyte deficiency symptoms so as to enhance the body's immune function;
7. Matrine is effective in dealing with trichomonad vaginitis, flagellate disease, amoeba dysentery and fungus dysentery, etc.
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