Customization: | Available |
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Certification: | ISO, FDA, Hahal, Food Manufacturing License, Business Licens |
Assay Method: | HPLC, UV |
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Product Name | 3,3'-Diindolylmethane |
CAS NO. | 1968-05-4 |
Other Names | Di-3-indolylmethane; Plant Indole; 3,3'-Methylenediindole;DIM |
Molecular Formula: | C17H14N2 |
Storage Conditions | Store in cool and dry places. Keep away from strong light and heat. |
Description
Acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol.It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells.DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor.The function of DIM and its derivatives as a new plant growth promoter has been studied in an eco-friendly system.Plant derived compound. Shows antitumor, antiproliferative effects and induces apoptosis.
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