World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract

Product Details
Customization: Available
Certification: ISO, FDA
Assay Method: HPLC, UV
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Number of Employees
39
Year of Establishment
2013-01-10
  • World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
  • World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
  • World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
  • World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
  • World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
  • World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
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Basic Info.

Model NO.
HWW2023122512
Application
Health Care Products, Medicine
State
Powder
Product Name
Valerian Extract
Latin Name
Valeriana Officinalis L
Used Part
Root
Appearance
Brownish Yellow Powder
Payment
T/T in Advance
Shelf Life
24 Months
Delivery Time
3-5 Working Days
Free Sample
Available
Transport Package
25kg/Drum
Specification
0.1%-0.8% Valerenic acids
Origin
Hunan, China
Production Capacity
2t/Month

Product Description

Product Details
Description:
It is a perennial and herbaceous plant which measures 50 to 100 cm in height. It is sparingly branched. The plant has light green central stem which is terete, stout, finely ribbed, pubescent and glabrous. An interior stem is hollow. Leaves are odd to pinnate having 4 to 9 pairs of sessile leaflets. Leaves measures about 8 inches long. Leaflets are linear to lanceolate to lanceolate to oblong in shape with smooth and sparingly dentate margins. An upper surface of leaflet is glabrous, medium and dark green whereas the lower surface is glabrous, slightly hairy and is pale. Lower and basal leaves possess longer petioles in comparison to upper leaves. Sometimes latter are sessile. The panicles of pedicles and peduncles are glabrous, pubescent and light green. Flowers are trumpet shaped, light pink or white measuring 4 mm long. Corolla has five spreading lobes and short green calyx have 3 stamens, 5 teeth and pistil with a style. Flowers are fragrant and blooms during summer for a month or two. Flowers are then replaced by achenes of 4 mm long, lanceoloid shape and slightly flattened with feathery hairs. It has rhizomatous and fibrous root system. Sometimes rhizomes produce colonies of clonal plants.


Flower and Fruit
Flowers are pink to white, androgynous which are in panicled cymes. Calyx is made up of 10 revolute tips. Corolla is in funnel shaped having five sectioned margin. Tube has a bump at a base. An ovary has three chambers and is inferior. There are three stamens. Fruit is indehiscent, ovate to oblong in shape, yellow and have 10 rayed tuft of white hair.

Leaves, stem and root
Plant grows about 500 to 100 cm high with a short and cylindrical rhizome having finger length and bushy round roots. Stem is unbranched and erect. Leaves are odd to pinnate having 11 to 23 lanceolate and indented-dentate leaflets. Upper ones are sessile and clasping with white sheath and lower ones are petiolate.

Health Benefits:
Acts as anticonvulsant
The extracts of Valerian featured anticonvulsant properties. The study was conducted to examine anticonvulsant properties of valerian extracts and valerenic acid and for determining whether the preparations of Valerian interact with anti-epileptic drugs activity. An adult zebrafish as an animal model was studied to find out the potential of antiepileptic drugs. In adult zebrafish, valerian and valerenic acid promote latency to PTZ induced seizure in a concentration dependent manner having more potent ethanolic extract. The extracts of ethanolic valenian potentiate antiepileptic effects of both clonazepa-m and phenytoin. Valerenic acid and valerian preparations interacted co-operatively having minimal concentration of clonazepa-m to promote latency to convulsions and upgrade survival. The results shows new therapeutic alternatives for epileptic patients.

Treatment for Parkinson's disease
Parkinson's disease is a neurodegenerative disorders which has become a common problem. The experiments reported cytoprotective effects of Valerian extracts for Parkinson's disease. Moreover, considering Parkinson's disease as a result of mitochondrial metabolic imbalance and oxidative stress, genomic approach for evaluation of possible underlying mechanisms of plant extract effect was added. The results brought new approach to Valerian extract and suggested that hesperidin and linarin have the ability to relieve oxidative stress effects during depletion of ATP because of its ability to bind SUR1. Additionally, vital role of valerenic acid and apigenin helps to prevent cortical hyperexcitation by activating neuronal cells from SN to release GABA on brain stem. Under oxidative stress, hyperexcitability and asphyxia, Valerina triggers various mechanisms for providing protection to neuronal cells.

Cardiovascular health
Valerian is a flowering plant which is renowned for its essential oils and iridoid compounds such as sesquiterpenes, monoterpenes, alkaloids, flavonoids, lignanoids and amino acids. Valerian displayed various biological activities such as lowering blood pressure, heart rate, antiarrhythmia, antimyocardial ischemia reperfusion injury and regulation of blood lipid levels. The review targets on chemical constituents as well as cardiovascular activities of Valerian. Valerian contains various bioactivities which have been discussed by its complex and various active ingredients. Though the effects of Valerian affected cardiovascular system, still further investigation is required for its mechanism of action.

Cure for insomnia
Insomnia has affected about one third of the population. It results in increasing rate of social disability, health care use and abseentism. The root extracts of Valerian are used to promote sleep and the sleep quality. The trials showed the use of Valerian to improve quality of sleep. The evidence shows that Valerian might promote quality of sleep without showing side effects. Further studies should show range of doses of standardized preparations of Valerian and involve standard measures of safety and sleep quality. Future studies of Valerian should be granted for high priority as insomnia is given high predominance worldwide.

Helpful for depression
Neuroimmune facts are the contributors of depression. Beside its therapeutic effects, Valerian showed anti-inflammatory properties. The study showed the effects of Valerian's hydro alcoholic extract on depression in ovalbumin sensitized rats. Results also supported traditional belief on the beneficial effect of Valerian on nervous system. Future studies are still needed to determine protective effect of Valerian.

Treatment for anxiety
Valerian root promotes amount of chemical known as gamma aminobutyric acid in brain. GABA assists in regulation of nerve cells and calms anxiety. Valerian root extract has valerenol and valerenic acid which acts as anti-anxiety agents. Valerian root possess anti-anxiety effects like prescription drugs without any serious side effects.

Reduce blood pressure
Valerian root helps to calm body as well as mind. It also lowers blood pressure by improving heart health. The active components found in Valerian root are effective for anxiety and stress management which helps to regulate blood pressure. High blood pressure increases the chances of getting stroke and heart attack. The supplements of Valerian root reduces blood pressure naturally and normalizes at healthy level that have positive impact on heart health.

Lower menstrual cramps
Valerian root has relaxing properties which provides relief from menstrual cramps. It lowers the severity as well as discomfort of menstrual cramps that has become common for women who suffer from PMS. Being a natural antispasmodic and sedative, it suppresses muscle spasms and relaxes muscles. Valerian root helps to calm severe uterine muscle contractions which cause terrible pain in women that experience during menstruation.

Reduce stress
Valerian root helps to lower anxiety and promotes length and quality of sleep with regular management of stress. Chronic stress makes feel anxiety which makes feel more stressed. With an improvement in GABA levels, it relaxes both body as well as mind. Valerian root lowers stress and improves quality of life. According to research, valerian root helps to restrain both psychological and physical stress.
 
Analysis Items Specifications Results  Methods used
Identification Positive Conforms TLC
Appearance Fine Dark Brown Powder Conforms Visual test
Odor & Taste Characteristic Conforms Organoleptic test
Particle Size 100% through 80 Mesh Conforms AOAC 973.03
Solubility Soluble in Ethanol & Water solution Conforms Visual
               
Valerianic acids NLT 0.2% 0.209% UV
Loss on Drying NMT 5.0% 3.43% 5g /105ºC /2hrs
Ash Content NMT 5.0% 3.47% 2g /525ºC /3hrs
Extract Solvents Ethanol & Water Conforms /
               
Heavy Metals NMT 10ppm Conforms Atomic Absorption
Arsenic (As) NMT 1ppm Conforms Atomic Absorption
Lead (Pb) NMT 1ppm Conforms Atomic Absorption
Cadmium (Cd) NMT 0.5ppm Conforms Atomic Absorption
Mercury(Hg) NMT 0.2ppm Conforms Atomic Absorption
               
Microbiological Data Total Plate Count<1,000cfu/g < 310 cfu/g GB 4789.2
Total Yeast & Mold<100cfu/g < 44 cfu/g  GB 4789.15
E. Coli to be negative Negative GB 4789.3
Staphylococcus to be  negative Negative GB 4789.10
Salmonella to be  negative Negative GB 4789.4
               
Packing and Storage Packed in fiber drum, LDPE bag inside. Net weight: 25kgs/drum. 
Keep tightly sealed, store away from moisture, strong heat and sunlight.
Shelf Life 2 years if sealed and stored in the recommended conditions.

World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract
World Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian ExtractWorld Well-Being Biotech ISO&FDA Certified CAS 109-52-4 0.1%-0.8% Valerenic Acids Valerian Extract

 

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