Customization: | Available |
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Certification: | ISO, FDA, Halal |
Assay Method: | HPLC, UV |
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Functions:
DIM is an effective radiation protector and mitigator by stimulating ATM-driven DDR-like responses and NF-κB survival signals. DIM can inhibit the invasion, angiogenesis, proliferation and induction of apoptosis of tumor cells by regulating signaling pathways such as AKT, NF-κB. It also inhibits estrogen-induced gene expression and causes endoplasmic reticulum stress. DIM can change estrogen metabolism and antagonize estrogen and androgen receptor activity.