UVA Ursi Extract 98% Alpha-Arbutin99% Beta-Arbutin90% 95% 98% Ursolic Acid Arctostaphylosuva-Ursi

• Certification: ISO, FDA, SGS, Halal, Sc&Bl
• Assay Method: HPLC, UV, Tlc
• Application Form: Tablet, Capsule, Granules
• Application: Food, Health Care Products, Medicine
• State: Brownish Yellow to off-White Powder
• Extract Source: Leaf
• Payment: T/T in Advance
• Shelf Life: 24 Months
• Delivery Time: 3-5 Working Days
• Free Sample: Available
• Transport Package: 25kg/Cardboard Drum I. D. 42cm X H. 52cm
• Specification: 98% Alpha-Arbutin 99% Beta-Arbutin 90% 95% 98% Urs
• Trademark: Shanghai, China
• Origin: China
• HS Code: 13021990
• Production Capacity: 20 Ton/Month

Product Description

Product Profile
Bearberry extract is extracted from the dried leaves of bearberry, a plant in the Ericaceae family. The main active ingredients are arbutin and ursolic acid. Ursolic acid not only resists a variety of carcinogens and carcinogens, but also inhibits the growth of a variety of malignant tumor cells. Arbutin is an inhibitor of tyrosinase in human melanocytes. Arbutin can effectively inhibit the activity of biological tyrosinase (tyrosinase) in the skin, block the formation of melanin, and directly bind to tyrosinase by itself. , accelerates the decomposition and excretion of melanin, thereby reducing skin pigmentation and removing spots and freckles. It is currently the main raw material commonly used in whitening cosmetics at home and abroad. Many countries in the world have applied arbutin to cosmetics.

Functions 
1. Antioxidant effect
Ursolic acid is a strong antioxidant. Its antioxidant effect has positive effects on human body's anti-aging, skin removal of freckles, pigmentation and beauty. It can be used in beauty and skin care products. Ursolic acid can obviously capture O2-, and shows a strong inhibitory effect on lipid peroxidation in liver microsomes and P45O monoamine oxidase system.
2. Anti-tumor effect
Ursolic acid has outstanding anti-tumor effects, has a broad anti-tumor spectrum, and has preventive and inhibitory effects on various stages of tumor formation and growth. It has resistance to a variety of carcinogens and carcinogens, thereby inhibiting the formation of cancer; it has obvious cytotoxic effects on a variety of malignant tumor cells, and has inhibitory effects on a variety of tumor cells in vivo and in vitro, and can reduce radiation, Adverse damage to the hematopoietic system after chemotherapy. Its anti-cancer and anti-cancer effects have attracted attention. It is foreseeable that ursolic acid may become one of the promising new anti-tumor drugs.
3. Effect on hepatitis
Ursolic acid has a significant protective effect on acute experimental liver injury. The clinical manifestations are a decrease in serum alanine aminotransferase levels, a significant reduction in liver cell degeneration and necrosis, and can quickly restore liver function. It has quick effects, short treatment courses, and stable effects. specialty. It has been clinically proven that ursolic acid can effectively treat viral hepatitis and is the main active ingredient in antiviral hepatitis drugs. Whether ursolic acid is used alone or in combination with other drugs in the preparation of drugs for the treatment of viral hepatitis, it has a significant effect in the treatment of viral hepatitis as long as it is prepared into drugs or health care drugs.
4. Antibacterial and antiviral effects
Ursolic acid can reduce cell viability, inhibit G+ and G- bacteria and inhibit fungal growth. It has obvious effects on killing and inhibiting Streptococcus mutans group and periodontal pathogenic bacteria. Ursolic acid can inhibit HIV-1 protease activity, enhance immune function, and exert anti-HIV effects.
5. Whitening and depigmentation effect
Arbutin has whitening activity. Its whitening mechanism is that arbutin competitively and reversibly inhibits tyrosinase, thereby blocking the synthesis of dopa and dopaquinone, thereby inhibiting the production of melanin, thereby achieving the whitening effect. But arbutin does not affect the expression and synthesis of tyrosinase. In addition, ursolic acid also has anti-malarial effects, which can significantly reduce the proliferation of malaria parasites; lower blood pressure, anti-hyperlipidemia, promote diuresis and lower blood sugar; it has certain toxicity to sperm and can be used as a contraceptive.
6.Other functions
Studies have shown that methanol extract of Uva ursifolia leaves (concentration 50%) has an inhibitory effect on tyrosinase. Arbutin has antibacterial, diuretic, astringent, anti-inflammatory and other effects. Hydroquinone aglycone and metabolites are produced in the urinary tract. In addition, ursolic acid has a diuretic effect, tannic acid has a strong astringent effect, has anti-cancer and anti-cancer effects, and allantoin can effectively resist skin ulcers.

Clinical Application
It is mainly used to treat urinary tract diseases, dermatitis, hypertension, congestive heart failure, trauma and diarrhea. Commercially available plant-based weight loss pills generally contain bearberry (astringent). However, bearberry usually makes urine turn green, but this is not harmful to the human body.
Bearberry preparations have the best antibacterial effect under alkaline conditions. Therefore, when taking bearberry preparations, you should avoid acidic foods, such as pickles, citrus, etc., and eat more alkaline vegetables (such as tomatoes) and apples and other fruits.
Bearberry is available medicinally in decoctions, tinctures, capsules and tablets. Put 3g of leaves in 150mL of water, decoct and take it for 1 day, which can be taken in 3 to 4 times. Tincture 3 times a day, 5mL each time. Capsules and tablets (containing 20% arbutin) take 250 to 500 mg daily, divided into three times.


Certificates of Analysis
 

Product Name:	Uva Ursi Extract		Latin name		Arctostaphylosuva-ursi
Part used	Leaf		Country of origin		China
Item		Specification		Result
Assay		90% Ursolic acid		HPLC
Physical & Chemical
Appearance		Off-white Powder		Conforms
Odor & Taste		Characteristic		Characteristic
Particle Size		90% through 80 mesh		Conforms
Loss on Drying		≤5.0%		1.32%
Ash		≤5.0%		2.11%
Heavy metals
As		≤2ppm		Conforms
Lead (Pb)		≤2ppm		Conforms
Cadmium(Cd)		≤1ppm		Conforms
Microbiological Test
Total Plate Count		NMT 1000cfu/g		Conforms
Total Yeast & Mold		NMT 100cfu/g		Conforms
E.Coli		Negative		Negative
Salmonella		Negative		Negative
Pesticide Residue		Negative		Negative