| Certification: | ISO, FDA, Hahal, Food Manufacturing License, Business Licens |
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| Assay Method: | HPLC, UV |
| Application Form: | Tablet, Capsule |
| Application: | Health Care Products, Medicine, Food & Beverage, Skin Care, Feed |
| State: | Powder |
| Extract Source: | Synthesis |
| Samples: |
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| Customization: |
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Audited Supplier | Description
Deoxyarbutin is a tyrosinase inhibitor (IC50 = 17.5 μM for mushroom tyrosinase).1 It reduces melanin content in isolated dark human melanocytes when used at a concentration of 1.56 μM.2 Topical administration of deoxyarbutin (5%) induces skin lightening in human skin mouse xenograft models. Deoxyarbutin also inhibits proliferation of B16/F10 murine melanoma cells (EC50 = 39.56 μM).3 It induces apoptosis and halts the cell cycle at the S phase in B16/F10 cells when used at a concentration of 50 μM. Deoxyarbutin (50 mg/kg) reduces tumor growth in a B16/F10 murine melanoma model.
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