Rheum Extract 10%-80% Rhein98% Rhein98% Chrysophanol Rhubarb Extract

• Certification: ISO, FDA
• Assay Method: HPLC, UV, Tlc
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Orange Yellow Powder
• Extract Source: Root
• Payment: T/T in Advance
• Shelf Life: 24 Months
• Delivery Time: 3-5 Working Days
• Free Sample: Available
• Transport Package: 25kg/Cardboard Drum I. D. 42cm X H. 52cm
• Specification: 10%-80% Rhein 98% Rhein 98% Chrysophanol
• Trademark: Shanghai, China
• Origin: China
• HS Code: 13021990
• Production Capacity: 20 Ton/Month

Product Description

Product Profile
Rhubarb extract is the dried root and rhizome extract of the Polygonaceae plant Rheum palmata, Rhubarb tangut or medicinal rhubarb. Rhubarb tastes bitter and cold, and returns to the stomach, liver and large intestine meridian. The active ingredients are anthraquinone compounds, including rhein and rhubarb. Emodin, chrysophanol, aloe-emodin, emodin methyl ether, etc., have the effects of scavenging oxygen free radicals, regulating blood lipids, anti-arteriosclerosis, anti-cancer, anti-aging, anti-psychotic, anti-bacterial and anti-inflammatory, hepatoprotective, choleretic, and anti-viral.

Function
1. Effect on digestive system
1.1. Purgative effect:
The main site of diarrhea is in the large intestine. The active ingredient in rhubarb diarrhea is anthracene glycosides, mainly sennosides. Sennoside is decomposed under the action of intestinal bacterial enzymes to produce anthrone rhein, which can stimulate the large intestinal mucosa, increase intestinal peristalsis and cause diarrhea. In addition, it can inhibit Na+ and K+-ATPase on the intestinal cell membrane, hinder Na+ transport, increase intestinal osmotic pressure, retain a large amount of water, promote intestinal peristalsis and diarrhea.

1.2. Choleretic and hepatoprotective effects:
Rhubarb extract can promote bile secretion, increase the content of bilirubin and bile acids in bile, relieve bile sphincter spasm, enhance duodenal and bile duct relaxation, and clear bile stasis in bile ducts and tiny bile canaliculi.

2. Effect on blood system
2.1. Hemostatic effect:
The hemostatic effect of rhubarb extract is precise and effective. The active ingredients are α-catechin and gallic acid. The mechanism of action is to promote the adhesion and aggregation of platelets; increase the number of platelets and fibrinogen content; reduce the activity of antithrombin III; and constrict the blood vessels in the injured area.
2.2. Blood lipid lowering effect:
Rhubarb extract reduces total cholesterol, triacylglycerols, low-density lipoprotein, very low-density lipoprotein, and lipid peroxidation levels. Making rhubarb into granules and taking it for 2 months showed a good lipid-lowering effect and no adverse reactions.
2.3. Blood-activating effect:
Rhubarb extract has a blood dilution effect, which may be due to the plasma osmotic pressure effect, which promotes the transfer of extracellular fluid into blood vessels, thereby diluting the blood, resulting in a decrease in blood cells, a decrease in blood viscosity, thereby enhancing microcirculation and achieving the purpose of promoting blood circulation. .
3. Anti-infection effect
Rhubarb extract has inhibitory effects on a variety of Gram-positive and -negative bacteria in vitro, and is especially sensitive to Paratyphoid and Shigella dysenteriae. It also has a certain killing effect on hepatitis B virus, various fungi, amoeba, and Trichomonas vaginalis. The main antibacterial ingredients are rhein, emodin and aloe-emodin. The antibacterial mechanism mainly inhibits the oxidation and dehydrogenation of bacterial sugar metabolism intermediates, inhibits the synthesis of proteins and nucleic acids, inhibits bacterial biological oxidase systems, and induces interferons.
4. Antipyretic effect
In the acute phase of acute or infectious diseases, the application of rhubarb extract treatment can have a cooling effect, and the cooling effect is stable, without adverse reactions such as sweating or collapse. Its antipyretic mechanism is to inhibit the synthesis of prostaglandin E in the body temperature center, reduce the content of cyclic glycoside nucleic acid, expand peripheral blood vessels and increase heat dissipation to achieve the purpose of cooling.
5. Immunomodulatory effect
Rhubarb extract has a two-way regulatory effect on immune function. It has varying degrees of immunosuppression. It has inhibitory or blocking effects on cellular immunity and humoral immunity. Long-term use can cause damage to the thymus, spleen, lymph nodes and other immune organs. shrink. In addition, rhubarb can increase the phagocytosis of mouse peritoneal macrophages, promote the body's production of interferon, and improve immunity, thereby achieving the purpose of eliminating viruses.
6. Other functions
The tannins contained in rhubarb have good antioxidant effects. Rhubarb polysaccharide also has obvious inhibitory effects on tumors, as well as lowering blood lipids, diuresis, anti-inflammatory effects, and antihypertensive effects.

Certificates of Analysis
 

Product Name:	Rheum Extract		Latin name		Rhubarb Extract
Part used:	Root		Country of origin		China
Item		Specification		Result
Assay		20% Rhein		HPLC
Physical & Chemical
Appearance		Orange yellow powder		Conforms
Odor & Taste		Characteristic		Characteristic
Particle Size		90% through 80 mesh		Conforms
Loss on Drying		≤5.0%		1.32%
Ash		≤5.0%		2.11%
Heavy metals
As		≤2ppm		Conforms
Lead (Pb)		≤2ppm		Conforms
Cadmium(Cd)		≤1ppm		Conforms
Microbiological Test
Total Plate Count		NMT 1000cfu/g		Conforms
Total Yeast & Mold		NMT 100cfu/g		Conforms
E.Coli		Negative		Negative
Salmonella		Negative		Negative
Pesticide Residue		Negative		Negative