Antibacterial 1%-10% Vitexin Antihypertensive Digestion Hypolipidemia Antibacterial and Cardiotonic 10% Maslinic Acid 5%-90%Hawthorn Flavonoids Hawthorn Extract

• Certification: ISO, FDA, Hahal, Bl, SGS, Food Manufacturing License
• Assay Method: HPLC, UV
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine, Cosmetics, Feed Additives, Functional Drink
• State: Brownish Yellow Powder
• Extract Source: Hawthorn
• Payment: T/T in Advance
• Shelf Life: 24 Months
• Delivery Time: 3-5 Working Days
• Free Sample: Available
• Transport Package: 25kg/Cardboard Drum I. D. 42cm X H. 52cm
• Specification: 5%-90% Flavonoids 10% Maslinic acid 1%-10% Vitexin
• Trademark: Shanghai, China
• Origin: China
• HS Code: 13021990
• Production Capacity: 20 Ton/Month

Product Description

 

Product Name: Hawthorn Extract 



Appearance: Brownish yellow powder



Specification: 5%-90% Flavonoids 
                        10% Maslinic acid
                         1%-10% Vitexin
 


Detection Method:HPLC 
 

Extraction Source

Hawthorn (Crataegus species ) is a small tree or shrub and it is a member of the rose family. It was hung over the doorway in the Middle Ages to prevent the entry of evil spirits. By the early 1800s, American doctors recognized the herb's medicinal properties and began using it to treat circulatory disorders and respiratory illnesses.

Certificates of Analysis
 

Product Name:	Hawthorn Extract	Latin Name:	Crataegus pinnatifida Bunge
Part used:	Hawthorn	Country of origin	China

Items	Specification	Result
Assay	10:1	HPLC
Organoleptic
Appearance	Fine Powder	Conforms
Color	Brownish yellow powder	Conforms
Odor	Characteristic	Conforms
Taste	Characteristic	Conforms
Physical Characteristics
Particle Size	NLT 100% Through 80 mesh	Conforms
Loss on Drying	≤12.0%	Conforms
Ash (Sulphated Ash)	≤0.5%	Conforms
Total Heavy Metals	≤10ppm	Conforms
Microbiological Tests
Total Plate Count	≤1000cfu/g	Conforms
Total Yeast & Mold	≤100cfu/g	Conforms
E.Coli	Negative	Negative
Salmonella	Negative	Negative
Staphylococcus	Negative	Negative

Efficacy and function

1. Cardiotonic effect
Hawthorn extract can increase myocardial contractility, increase cardiac output, and slow down heart rhythm.

2. Effect on coronary blood flow and myocardial oxygen consumption
Hawthorn extract and its total flavonoids can increase coronary blood flow, reduce myocardial oxygen consumption and myocardial oxygen utilization.

3. Antihypertensive effect
Hawthorn ethanol extract has a long-lasting antihypertensive effect.

4. Hypolipidemic effect
Different extracted parts of hawthorn have certain lipid-lowering effects on various high-fat models caused by different animals, and can antagonize the increase in serum cholesterol and triglyceride levels caused by high-fat feeds.

5. Promote digestion
Hawthorn extract can promote the secretion of digestive enzymes in the stomach and promote digestion. The lipase contained in it can promote the decomposition and digestion of fat; it contains a variety of organic acids and vitamin C, which can increase the activity of pepsin and promote the digestion of protein. Hawthorn extract has a certain regulatory effect on gastrointestinal function, has an inhibitory effect on hyperactive rabbit duodenal smooth muscle, and has a slight increase in contraction of relaxed rat gastric smooth muscle.

6. Antibacterial effect
Hawthorn extract has strong antibacterial effects against Shigella, Shigella flexneri, Sonnei and other dysentery bacteria and Escherichia coli. It also has antibacterial effects on Staphylococcus aureus, Group B Streptococcus, Escherichia coli, Proteus, Bacillus anthracis, Bacillus diphtheriae, Bacillus typhi, Pseudomonas aeruginosa, etc. Generally, it is more effective against Gram-positive bacteria than Gram-negative bacteria. The processing method seems to have no effect on the antibacterial effect. There is no significant difference in the antibacterial effect of raw coke hawthorn on Shigella dysenteriae, Proteus and Escherichia coli.

7.Immune enhancement effect
Experiments have confirmed that hawthorn injection can significantly enhance the humoral and cellular immunity of rabbits, and significantly enhance serum lysozyme content, serum hemagglutination antibody height, cardiovascular T lymphocyte E rosette formation rate, and blood T lymphocyte transformation rate. effect.

8. Hypolipidemic effect
Hawthorn has a significant effect on lowering blood cholesterol in young white rats. The reduction rate can reach 30.8%. It is also effective in treating hypertriglyceridemia. Its blood-lipid-lowering effect, through research on cholesterol synthase (HMGR) and its decomposition rate-limiting enzyme 7α-hydroxylase, found that hawthorn reduced the activity of HMGR in guinea pig liver cell microsomes and small intestinal mucosa, by more than 60%, and It has no stimulating effect on hepatocyte microsomal 7α-hydroxylase activity. It shows that it mainly inhibits the synthesis of cholesterol.

9. Inhibit platelet aggregation
Experiments have shown that hawthorn decoction has certain effects on inhibiting platelet aggregation in vitro, with an IC50 of 1.388%. When hawthorn is combined with Alisma, it can significantly improve the platelet aggregation inhibitory effect of Alisma.

10. Effect on uterine contraction
Hawthorn extract has the effect of contracting the uterus and promoting the recovery of the uterus. The effect of contracting the uterus can promote the discharge of blood clots in the uterine cavity. In addition, it has the effect of dilating blood vessels, relieving blood stasis, and has a certain sedative effect. These effects are the pharmacological basis for its use in the treatment of postpartum stasis and abdominal pain.

Application
Hawthorn extract has very good water solubility and is suitable for food, beverage, health care products, feed and other industries. It can be used as additives, liquids, tablets, and capsules without any problem.

Hawthorn extract is a pure natural plant extract that does not contain any hormones, antibiotics, or chemical components. In the current environment where antibiotics are banned in livestock breeding, it is playing a huge commercial role.