Product Profile
Agaricus blazei extract is extracted from the fruiting bodies and mycelium of Basidiomycetes, subphylum fungi, class Agaricaceae, mushrooms of the family Agaricaceae, and contains rich biologically active substances, including polysaccharides, sterols, and nucleic acids. Categories, unsaturated fatty acids, etc., integrating food, beauty, medical treatment, health care and other functions. It has the effects of inhibiting the growth of tumor cells, anti-tumor, lowering blood sugar, improving diabetes, lowering cholesterol, and improving arteriosclerosis. Among them, α-(l,3) glucan with β-(1,6) branch can directly kill tumors by inducing apoptosis of tumor cells.
Function and effect
1. Anti-tumor activity
Agaricus blazei extract contains a variety of water-soluble and water-insoluble polysaccharides with obvious anti-tumor activity. Among them, the water-soluble polysaccharide FA-I-α-β is mainly composed of (1-6)β-D-glucan and (1-3)β-D-glucan. The main anti-tumor mechanism is to indirectly exert anti-tumor effects by stimulating the body's immune system, improving and adjusting the body's internal defense system, that is, it works through host mediation. By acting on immune cells, it promotes the production of cytokines and activates complement, thereby having anti-tumor activity.
2. Enhance the body's immune function
The polysaccharide extracted and isolated from Agaricus blazei is an immune enhancer. It can not only activate the activity of T cells, B cells, MΦ, NK cells, CTL cells, LKA cells and other immune cells, but also activate the reticuloendothelial system (RES) to phagocytose and eliminate aging. The role of cells, foreign bodies and pathogens can also promote the production of IL-1, IL-2, TNF-α, INF-r, N0, etc., regulate the formation of the body's antibodies and complement, and improve the body's anti-tumor immunity. In addition, the anti-tumor, anti-radiation, anti-aging and other activities of polysaccharides are all related to the non-specific immune enhancement of polysaccharides.
3. Liver protection function
Agaricus blazei polysaccharide has anti-hepatitis effect. The anti-inflammatory effect of Agaricus Blazei Murill polysaccharide is mainly to inhibit the biosynthesis and release of prostaglandin E2, and also inhibit the production and release of inflammatory mediators such as histamine, 5-hydroxytryptamine and bradykinin. Polysaccharides also have a protective effect on liver damage. Agaricus agaricus water extract has a protective effect on hepatotoxicity induced by different doses of diethylnitrosamine and on the liver of rabbits exposed to carbon tetrachloride.
4. Antioxidant effect
Agaricus blazei polysaccharide can increase the activity of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX), reduce the content of lipid peroxides, and eliminate them at low concentrations. The role of free radicals.
5. Inhibit mutation
Agaricus blazei extract has a significant inhibitory effect on the mutagenic effects of hair dyes, strong carcinogens 2-AF, cyclophosphamide and benzo(a)pyrene in vitro.
6. Affects hematopoietic function
Agaricus Blazei Murill polysaccharide can promote the proliferation of normal hematopoietic stem and progenitor cells. Different doses of the same drug have different effects on hematopoietic stem and progenitor cells.
7. Improve blood flow
The aqueous extract of Agaricus blazei can significantly reduce the whole blood viscosity and plasma viscosity of blood stasis rats, and has a certain improvement effect on the hemorrheology of blood stasis model rats. Agaricus blazei ω-6 polyunsaturated fatty acid (ω-6APFA) can prolong the coagulation time of mice and increase blood fluidity. It has good effects on improving blood viscosity, inhibiting thrombosis and activating blood circulation and removing blood stasis. The effect is better than commercially available prophylaxis. And natural soybean phospholipid capsules (NSPC) that alleviate such diseases. ω-6APFA can also prevent lipid deposition in the liver and arterial walls, and has a significant blood-lipid-lowering effect on hyperlipidemia rats.
Certificates of Analysis
| Product Name: |
Agaricus Blazei Extract |
Latin Name: |
Agaricus Blazei Murrill |
| Part used: |
Fruiting body |
Country of origin |
China |
| |
| Item |
Specification |
Result |
| Aaasy |
15% Polysaccharide |
HPLC |
| Physical & Chemical |
| Appearance |
Brownish yellow powder |
Conforms |
| Odor & Taste |
Characteristic |
Characteristic |
| Particle Size |
90% through 80 mesh |
Conforms |
| Loss on Drying |
≤5.0% |
1.32% |
| Ash |
≤5.0% |
2.11% |
| Heavy metals |
| As |
≤2ppm |
Conforms |
| Lead (Pb) |
≤2ppm |
Conforms |
| Cadmium(Cd) |
≤1ppm |
Conforms |
| Microbiological Test |
| Total Plate Count |
NMT 10000cfu/g |
Conforms |
| Total Yeast & Mold |
NMT 1000cfu/g |
Conforms |
| E.Coli |
Negative |
Negative |
| Salmonella |
Negative |
Negative |
| Pesticide Residue |
Negative |
Negative |
Audited Supplier 
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