| Customization: | Available |
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| Certification: | ISO, FDA |
| Assay Method: | HPLC, UV |
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Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.
EGT is accumulated into different cellular compartments via its specific transporter OCTN-1,abundantly expressed in mitochondrial DNA is especially vulnerable to stress because unlike nuclear DNA,there are no histones to protect mitochondrial DNA.Reactive oxygen species,like superoxides O2- generated in the mitochondria by respiration,are directly scavenged by EGT.EGT presents in the cytoplasm also scavenges a variety of ROS and reactive nitrogen species.EGT absorbs UV radiation and prevents DNA breaks and mutations.
Applications
1. Ergothioneine liver damage treatment
2. Ergothioneine cataracts treatment.
3. Ergothioneine alzheimer's disease treatment.
4. Ergothioneine diabetes treatment.
5. Ergothioneine heart disease treatment.
6. Ergothioneine preventing wrinkles and reducing signs of aging, when applied to the skin.
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