China Factory Free Sample Skin Care Emodin 98% Polygonum Cuspidatum 98% Giant Knotweed Extract Resveratrol 50%-98% Polygonum Cuspidatum Extract

• Certification: ISO, FDA, Halal
• Assay Method: HPLC, UV
• Application Form: Lotion, Tablet, Capsule
• Application: Food, Health Care Products, Medicine, Cosmetics
• State: Powder
• Extract Source: Root
• Model NO.: 501-36-0
• Product Name: Polygonum Cuspidatum Extract
• Latin Name: Reynoutria Japonica Houtt
• Appearance: off-White Powder
• Used Part: Root
• Shelf Life: 2 Years
• Delivery Time: 7- 10days
• Sample: Available
• Transport Package: 1kg/Foil Bag, 25kgs/Drum
• Specification: Polygonum Cuspidatum 98% Resveratrol 50%-98%
• Trademark: World Well-Being
• Origin: Hunan, China
• Production Capacity: 1000kgs/Month

Product Description

Giant knotweed is widely grown throughout Japan and is foraged as a wild edible vegetable. The root of Polygonum cuspidatum, were widely used in traditional Chinese and Japanese medicine. It is also known to be a rich source of resveratrol, which is a natural polyphenol. Emodin, physcion, citreorosein, rhein, fallacinol, questin, phenylpropanoides , polyphenols, and tannins are major active components present in this root. It is a good source of reveratrol, and carotenoids that act as a potent antioxidant that minimizes the effect of harmful oxidative stress. It is good for the heart, and gastrointestinal tract health.Resveratrol, a non-flavonoid polyphenolic organic compound, is an antitoxin produced by many plants when stimulated.
Resveratrol can act as the strongest activator of silencing messengers and is involved in the regulation of the average life span of organic organisms. It can regulate blood cholesterol levels by binding to estrogen receptors in humans and inhibit platelets from forming clots that adhere to blood vessel walls, thereby inhibiting and reducing the occurrence and development of cardiovascular disease and reducing the risk of cardiovascular disease in humans.
 

 

Product Name: Polygonum cuspidatum Extract
Plant Part Used: Root 
Active ingredient: Resveratrol
Specification: 10%-98% HPLC 
Appearance: Off-white powder

CAS No.: 501-36-0

 

Product Name: Polygonum cuspidatum Extract
Plant Part Used: Root 
Active ingredient:  Emodin  
Specification: 80%/98% HPLC 
Appearance: Brown yellow powder

CAS No.: 518-82-1

Certificates of Analysis                                                         

PRODUCT SPECIFICATIONS
Product Name:	Polygonum cuspidatum extract
Botanic  Name:	Polygonum cuspidatum Sieb.et Zucc
Scientific name(Family/Genus/Species)	Polygonaceae/Reynoutria/P. cuspidatum
Part of plant	Root
Solvent extraction	20% Water & 80% ethanol
Country of Origin:	China
Excipent	None
ANALYSIS ITEMS	SPECIFICATION	TEST METHOD
Appearance	Fine powder	Organoleptic
Color	White	Visual
Odour & Taste	Characteristic	Organoleptic
Identification	Identical to R.S. sample	HPTLC
Resveratrol	NLT 98.0%	HPLC
Solubility	Not soluble in water	Organoleptic
Hydrocarbons PAHs	≤ 50 ppb -Reg.UE 1933/2015	GC-MS
Benzo(a)pyren	≤ 10 ppb -Reg.UE 1933/2015	GC-MS
Radioactivity	≤ 600 Bq/Kg -Reg. CE 1409/2009	Gamma spectrometry
Apparent density	0.4-0.7g/ml	Eur.Ph. <2.9.34>
Sieve Analysis	100% through 80 mesh	USP39 <786>
Loss on drying	≤ 5.0%	Eur.Ph.9.0 [2.5.12]
Total Ash	≤ 5.0%	Eur.Ph.9.0 [2.4.16]
Lead (Pb)	≤ 3.0 mg/kg	Eur.Ph.9.0<2.2.58>ICP-MS
Arsenic (As)	≤ 1.0 mg/kg	Eur.Ph.9.0<2.2.58>ICP-MS
Cadmium(Cd)	≤ 1.0 mg/kg	Eur.Ph.9.0<2.2.58>ICP-MS
Mercury(Hg)	≤ 0.1 mg/kg -Reg.EC629/2008	Eur.Ph.9.0<2.2.58>ICP-MS
Heavy metal	≤ 10.0 mg/kg	Eur.Ph.9.0 <2.4.8>
Solvents Residue	Conform Eur.ph. 9.0 <5,4 > and EC European Directive 2009/32	Eur.Ph.9.0<2.4.24>
Pesticides Residues	Conform Regulations(EC) No.396/2005 including annexes and successive updates Reg.2008/839/CE	Gas Chromatography
Aerobic bacteria(TAMC)	≤1000 cfu/g	USP39 <61>
Yeast/Moulds(TAMC)	≤100 cfu/g	USP39 <61>
Bile-tol.gram- b./Enterobact.:	≤100 cfu/g
Escherichia coli:	Absent in 1g	USP39 <62>
Salmonella spp:	Absent in 25g	USP39 <62>
Staphylococcus aureus:	Absent in 1g
Listeria Monocytogenens	Absent in 25g
Aflatoxins B1	≤ 5 ppb -Reg.EC 1881/2006	USP39 <62>
Aflatoxins ∑ B1, B2, G1, G2	≤ 10 ppb -Reg.EC 1881/2006	USP39 <62>

Functions:
1.Resveratrol - Anti-cancer effect.
2.Resveratrol - Cardiovascular protective effects.
3.Resveratrol - Estrogen regulation effects.
4.Resveratrol - Anti-bacterial, anti-oxidant, anti-aging effects.
5.Resveratrol - Enhance the endurance ability of muscle effect.
6.Resveratrol - Anti-oxidant, anti-canner, protect the nervous system.

(1)Health benefits
Japanese Knotweed is an excellent source of vitamin C and vitamin A. It also offers potassium, zinc, phosphorus and manganese. It is a great source of resveratrol which lowers bad cholesterol and chances of heart attacks. It also acts as anti-inflammatory which assist immune system to fight infections, relieves arthritis and prevents the body from neurotoxin damage.

(2)Cognitive problems
Japanese knotweed has positive effect on the cognitive disorders such as dementia and Alzheimer's disease. It is due to resveratrol content in this herb. It provides preventative effect on the neurodegenerative process which affects the neural pathways. Antioxidants eliminates free radicals and plaque which affects the mental function. Resveratrol energizes the brain pathways which prevents the health ailments.

(3)Heart ailments
The food rich in fat increases the chances of heart problems and cardiovascular conditions such as high cholesterol. Japanese knotweed possesses resveratrol which helps to deal with such conditions. Red wine is drunk in large amounts in France due to which heart conditions are not common there. One should add Knotweed to the diet to get the heart protective properties. (2)

(4)Lowers blood pressure
Resveratrol is able to reduce the fat and balances the blood pressure. It reduces the heart strain, stress and also reduces the blood pressure which lowers the chances of strokes and heart attacks by dilating the blood vessels and arteries hindering blood clots. 

(5)Gastrointestinal health
Japanese knotweed helps to treat the stomach problems such as bloating, constipation, inflammation, bloating, chronic pain and cramps. Resveratrol found in Japanese knotweed reduces the gastrointestinal distress and acts as a laxative which assists in the normal process of digestive system. 

(6)Prevent cancer
Japanese knotweed possesses anti-cancer properties. Resveratrol is beneficial against carcinogens which lead to cancer such as colon, prostate, thyroid and breast cancer. Research is still going on but the early found results are satisfactory which adds a reason to use in order to prevent health. 

(7)Controls insuli
The poor diet is responsible for the improper regulation of insuli levels and prosper insuli resistance. It results in diabetes and health ailments. The addition of Japanese Knotweed helps to avoid these conditions. Japanese knotweed possesses resveratrol which prevents the development of insuli resistance and also regulates the level of blood sugar. (6)

Applications:

 

1. Treats Benign Prostatic Hypertrophy (BPH)

The most common form of an enlarged prostate is benign prostatic hyperplasia - or BPH. The prostate gland can become inflamed or enlarged as men get older. The prostate then compresses the urethra, leading to difficulty with urination that results in bladder infections or bladder stones. BPH can be caused by a variety of circumstances, including hormonal changes (such as excess estrogen), deteriorating blood vessels and a zinc deficiency.

The American Urological Association reports that by the age of 60, over 50 percent of men will have BPH, and by age 85, 90 percent of men will have this condition. To add to this, one-fourth of these men will develop moderate to severe lower urinary tract symptoms that will greatly affect their quality of life.

Other treatments for BPH, alpha blockers and 5-alpha-reductase inhibitors cause sexual dysfunctions themselves - while saw palmetto is a natural supplement that doesn't have a long list of side effects. That makes it one of the best sources to improve prostate health the natural way.

One 2012 study conducted in Switzerland analyzed 82 patients in an eight-week trial; the patients took  one capsule of 320milligrams saw palmetto extract daily. At the end of the treatment, the International Prostate Symptom Score was reduced from 14.4±4.7 to 6.9±5.2. Investigators' and patients' assessments confirmed the good efficacy, and treatment was very well-tolerated and accepted by the patients.

2. Reduces Risk of Prostate Cancer

A systematic literature review of 11 studies identified saw palmetto supplements as one of the five commonly used forms of alternative medicine by men with prostate cancer.

Studies have also found that saw palmetto inhibits the growth of prostatic cancer cells and may destroy dangerous cells. A study conducted at the Department of Biochemistry and Molecular Biology in Beijing found that saw palmetto induced growth arrest of prostate cancer LNCaP, DU145 and PC3 cells and down-regulated DHT, the hormone that leads to prostate enlargement.

Another interesting note about saw palmetto is the research that has been done to measure its effect on post-surgery recovery time. Prostate surgery (known as transurethral resection of the prostate or TURP) can require a lengthy recovery period, but research shows that taking 320 milligrams of saw palmetto daily for two months before prostate surgery can reduce the time spent in surgery. It also helps with blood loss, the development of problems during surgery and the total time spent in the hospital.