| Customization: | Available |
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| Certification: | ISO, FDA, Hahal, Food Manufacturing License, Business Licens |
| Assay Method: | HPLC, UV |
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Description 1-Octacosanol is a very long-chain fatty alcohol that has diverse biological activities, including antibacterial, antifungal, anti-inflammatory, and antioxidative properties. It is active against the bacteria K. pneumoniae, S. flexneri, S. typhi, and E. faecalis (MICs = 4, 8, 2, and 32 µg/ml, respectively), as well as the pathogenic fungi T. ajelloi and T. rubrum (MICs = 4 and 32 µg/ml, respectively), but not the yeast C. albicans, C. lusitaniae, or C. krusei. It reduces the expression of TNF-α, inducible nitric oxide synthase (iNOS), IL-1β, and IL-6 in RAW 264.7 cells stimulated with LPS when used at concentrations of 30 and 100 µg/ml. 1-Octacosanol (100 mg/kg per day) increases body weight, decreases diarrhea and hematochezia, and improves histopathological and morphological changes in the colon in a mouse model of ulcerative colitis induced by dextran sulfate sodium. 1-Octacosanol (10, 50, or 100 mg/kg) reduces carbon tetrachloride-induced increases in serum transaminase, hepatic myeloperoxidase, and hepatic xanthine oxidase activity, as well as lipid peroxidation, in a rat model of acute liver injury progression.It also reverses decreases in hepatic superoxide dismutase and catalase activity, as well as glutathione (GSH) levels, in the same model. Benefits: (1) To strengthen stamina,vigour and physical strength; (2) To improve the reactive sensitivity; (3) To improve the strength; (4) To promote function of sex hormone,ease the pain of muscle; (5) To improve the function of cardiac muscle, (6) To reduce cholesterol,blood fat and systolic pressure; (7) To improve the organism metabolism. |
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