Customization: | Available |
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Certification: | ISO, HACCP |
Assay Method: | HPLC, UV |
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Description:
Herba houttuyniae has been used as a constituent of herval medicine prescripti ons for the treatment of inflammation, cancer, and other diseases.
In the present study, we investigated the cellular effects of herba houttuyniae extract (HHE) and the signal pathways of HHE-induced apoptosis in HL-60 human promyelocytic leukemia cell line.
HHE treatment caused apoptosis of cells as evidenced by discontinuous fragmentation of DNA, the loss of mitochondrial membrane potential, release of mitochondrial cytochrome c into the cytosol, activation of procaspase-9 and caspase-3, and proteolytic cleavage of poly(ADP-ribose) polymerase.
Pretreatment of Ac-DEVD-CHO, caspase-3 specific inhibitor, or cyclosporin A, a mitochondrial permeability transition inhibitor, completely abolished HHE-induced DNA fragmentation.
Function:
(1) Lung abscess with purulent expectoration
(2) Heating in the lung with cough and dyspnea
(3) Acute dysentery; Acute urinary infection; Carbuncles and sores
Herba houttuynia has been used as a constituent of herbal medicine prescriptions for the treatment of inflammation, cancer, and other diseases.