Customization: | Available |
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Certification: | ISO, FDA |
Assay Method: | HPLC, UV, Tlc |
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Swertia is a genus in the gentian family. Swertiamarin is used as an active ingredient derived from Swertiapatens (Swertia davida or Swertia bimaculata). Swertiamarin is a representative constituent of many crude drugs, which are marketed in Japan and other countries and these crude drugs are normally evaluated by their high swertiamarin content (Takei et al., 2001). It has very low toxicity and is a safe and effective antispastic agent. It showed sedative effect in mice, pigeons and rabbits and induced sleep in mice (Mandal et al., 1998). Its antibacterial, brine shrimp lethality and anticholinergic activities were also reported (Kumarsamy et al., 2003). The study results prove that swertiamarin possess both peripheral and central antinociceptive activity. Swertiamarin are being used to relieve pain. It mainly treats the hepatitis, Oxidation resistance, Antivirus,Increase Immune Function.
Certificate of Analysis:
Analysis Items | Specifications | Results | Methods used | ||||
Identification | Positive | Conforms | TLC | ||||
Appearance | Fine Dark Brown Powder | Conforms | Visual test | ||||
Odor & Taste | Characteristic | Conforms | Organoleptic test | ||||
Bulk Density | 45-55g/100ml | Conforms | ASTM D1895B | ||||
Particle Size | 98% through 80 Mesh | Conforms | AOAC 973.03 | ||||
Solubility | Soluble in Ethanol and Methanol | Conforms | Visual | ||||
Assay | NLT 30% Swertiamarine | 30.12% | HPLC | ||||
Loss on Drying | NMT 5.0% | 4.09% | USP | ||||
Ash Content | NMT 5.0% | 1.09% | 2g /525ºC /3hrs | ||||
Extract Solvents | Ethanol & Water | Conforms | / | ||||
Solvent Residues | NMT 0.05% | Conforms | USP-GC | ||||
Heavy Metals | NMT 10ppm | Conforms | Atomic absorption | ||||
Arsenic (As) | NMT 2ppm | Conforms | Atomic absorption | ||||
Lead (Pb) | NMT 2ppm | Conforms | Atomic absorption | ||||
Cadmium (Cd) | NMT 0.5ppm | Conforms | Atomic absorption | ||||
Mercury (Hg) | NMT 0.2ppm | Conforms | Atomic absorption | ||||
BHC | NMT 0.1ppm | Conforms | USP-GC | ||||
DDT | NMT 0.1ppm | Conforms | USP-GC | ||||
Acephate | NMT 0.2ppm | Conforms | USP-GC | ||||
Parathion-ethyl | NMT 0.2ppm | Conforms | USP-GC | ||||
PCNB | NMT 0.1ppm | Conforms | USP-GC | ||||
Function:
1.Swertia Chirata Extract has protecting liver,detoxification, blood enzyme,reduce liver splenomegaly, enhance liver area of macrophage phagocytosis function.Swertiamarin has obvious inhibition hepatoma carcinoma cell function.
2.Swertia Chirata Extract direct effects on intestinal smooth muscle and spasmolysis.
3.Swertia Chirata Extract has significant analgesic and sedation,can treat gastrointestinal pain.
4.Swertia Chirata Extract have anti-inflammatory, antiviral effect,Can expand capillaries, and
activate or promote skin cell enzyme system, improve the biochemical function of skin cells.
1.Applied in the pharmaceutical field as medicine l raw materials;
2.Applied in the health care products field;
3.Applied in the food and beverage industry field.