Natural Grape Seed Extract 95% 98% Proanthocyanidins 40% Polyphenols Vitis Vinifera Linn. Food Grade Cosmetic Grade Pharmaceutical Grade

• Certification: ISO, FDA
• Assay Method: HPLC, UV, Tlc
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Brownish Red Powder
• Extract Source: Seed
• Model NO.: Grape Seed Extract
• Payment: T/T in Advance
• Shelf Life: 24 Months
• Delivery Time: 3-5 Working Days
• Free Sample: Available
• Transport Package: 25kg/Cardboard Drum I. D. 42cm X H. 52cm
• Specification: 95% 98% Proanthocyanidins 40% Polyphenols
• Trademark: Shanghai, China
• Origin: China
• HS Code: 13021990
• Production Capacity: 20 Ton/Month

Product Description

Product Profile
Medicinal value of grape seeds
Grape seeds have the effects of "supplementing qi and blood, strengthening muscles and bones, promoting urination, and treating weak qi and blood, cough due to lung deficiency, palpitations and night sweats, rheumatic arthralgia, gonorrhea, and edema." Modern research shows that the procyanidin glycosides in grape seed extract have anti-inflammatory properties. With the function of oxidizing and lowering cholesterol levels, it is a natural antioxidant with great potential and can be used to prevent and treat high cholesterol, atherosclerosis, cataracts, gastric ulcers, intestinal adenocarcinoma, Ehrlich ascites cancer, etc.

The main pharmacological effects are as follows:
1. Antioxidant effect: The polyphenols in grape seed extract include phenolic hydroxyl groups of proanthocyanidins and gallic acid, which provide hydrogen atoms and have a specific and powerful antioxidant effect. The ability to neutralize iron ions and oxygen that attack lipids is 15 to 25 times that of VB, and its free radical scavenging effect is stronger than antioxidants such as VC and VE.
2. Anti-radiation effect: It can inhibit lipid peroxidation caused by radiation.
3. Anti-inflammatory effect: The main component is proanthocyanidins, whose antioxidant activity can inhibit the synthesis and release of inflammatory factors such as histamine, 5-hydroxytryptamine, prostaglandins and leukotrienes, and inhibit the release of basophils and mast cells. Granules can also inhibit the activity of histamine decarboxylase and limit the action of hyaluronidase.
4. Cataract prevention effect: The main component of cataract prevention is catechin; grape seed extract can improve the vision of patients with myopic retinal non-inflammatory changes and improve eye fatigue.
5. Anti-cancer effect: It has cytotoxicity to MCF-7 human breast tumor cells, A-427 human lung cancer cells and CRL1739 human gastric adenocarcinoma cells, and can prevent the carcinogenic effects of intestinal chemical carcinogens.
6. Anti-atherosclerosis effect: Food containing 2.5% grape seed extract can reduce the level of cholesterol ester peroxide in the serum of experimental animals, and can also reduce low-density lipoprotein to fight atherosclerosis. It can improve blood rheology indicators and platelet aggregation.
7. Cholesterol-lowering effect: Gallic tannins can reduce plasma total cholesterol, triglyceride, low-density cholesterol and very-low-density cholesterol levels, and increase high-density cholesterol levels.
8. Anti-ulcer effect: The oligomeric proanthocyanidins in grape seed extract can protect gastric mucosal damage. Proanthocyanidins have the effect of scavenging free radicals on the gastric surface and protecting the gastric wall.
9. Anti-mutagenic effect: It can reduce the incidence of mitochondrial mutations and nuclear mutations. Introduction: Grape seed extract is a polyphenolic substance extracted from grape seeds. The main active ingredient is a low molecular weight polymer of proanthocyanidins. It is an edible product. It is a powerful antioxidant and an efficient free radical scavenger. Used in food supplements, health foods and cosmetics, etc.

Certificates of Analysis
 

Product Name:	Grape Seed Extract		Latin Name:		Vitis vinifera Linn.
Part used:	Seed		Country of origin		China
Item		Specification		Result
Assay		10% Polysacharides		Conforms
Physical & Chemical
Appearance		Brownish red powder		Conforms
Odor & Taste		Characteristic		Characteristic
Particle Size		90% through 80 mesh		Conforms
Loss on Drying		≤5.0%		1.32%
Ash		≤5.0%		2.11%
Heavy metals
As		≤2ppm		Conforms
Lead (Pb)		≤2ppm		Conforms
Cadmium(Cd)		≤1ppm		Conforms
Microbiological Test
Total Plate Count		NMT 1000cfu/g		Conforms
Total Yeast & Mold		NMT 100cfu/g		Conforms
E.Coli		Negative		Negative
Salmonella		Negative		Negative
Pesticide Residue		Negative		Negative