World Well-Being High Quality 50% 98% Kaempferol Powder Fructus Sophorae Extract

• Certification: ISO, FDA, Sc(OS)/Jy/Kosher/Halal
• Assay Method: HPLC, UV
• Application Form: Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Whole
• Model NO.: HWW-2022111871
• Transport Package: 25kg/Drum
• Specification: 98%
• Trademark: World Well-being
• Origin: Hunan
• Production Capacity: 10t/Month

Product Description

Item	Description
Product Name	Kaempferol
Extract from	Fructus Sophorae
Specification	98% OEM/ODM optional
Extraction Type	Solvent Extraction
Appearance	Powder
Test Method	HPLC
Package	25kgs/drum
Shelf Life	24 Months Properly Storage

 
  Kaempferol, a natural flavonol, is a type of flavonoids that make up about 60% of all polyphenols. Such as quercetin, kaempferol. It is isolated from tea, broccoli, delphinium, witch hazel, grapefruit, Brussels sprouts, kaempferen, and other plants.
Kaempferol has strong antioxidant properties, which can remove excess superoxide free radicals in the human body and prevent oxidative damage to DNA and cells. It has anti-tumor, anti-inflammatory, anti-aging and other pharmacological effects. Kaempferol also has the functions of treating diabetes and osteoporosis.

Function
Anti-cancer and Anti-cancer
Kaempferol has anti-cancer and anti-cancer effects. Studying the effect of kaempferol on the growth and apoptosis of human liver cancer cell Huh7 under the conditions of in vitro test, proved that it may be because kaempferol increased the activity of Caspas-3 and induced the apoptosis of cells, so that the human liver cancer cells Huh7 suppressed. Kaempferol was applied to human gastric cancer cell MGC-803 (in vitro test), and DAPI staining was observed under a fluorescent microscope.
It was found that the chromatin of the nucleus was condensed, and the nucleus was dissolved and irregular in shape. According to the results of the MIT method, it was found that kaempferol It can inhibit the proliferation of cancer cells. According to the comet electrophoresis method to observe the cancer cells after the action of kaempferol, it is found that most of the cancer cells are in the shape of comet tails, and the results of cell DNA damage are obtained. Finally, it is concluded that kaempferol can inhibit human gastric cancer cells proliferation.
Prevention and Treatment of Diabetes
In addition to the anti-cancer effect, kaempferol also has the effect of preventing and treating diabetes. The researchers established a mouse experimental model to verify the effect of kaempferol on lowering blood sugar and blood lipids in diabetic mice.
The diabetic model mice fed with kaempferol and the diabetic mice fed with Xiaoke pill were used as a control experiment, respectively. Determination of serum triglycerides, total cholesterol, blood sugar, malondialdehyde levels and the activities of glutathione peroxidase and superoxide dismutase in diabetic model mice showed that kaempferol can effectively reduce the The levels of serum triglycerides, total cholesterol, blood sugar and malondialdehyde can significantly increase the activities of glutathione peroxidase and superoxide dismutase in serum, with 10 mg/(kg bw d) as the Optimal dosage. Kaempferol can delay the development of diabetes. All the above studies have proved the therapeutic effect of kaempferol on diabetes.
Protection against Damaged Cells
 Acute liver failure is caused by a large number of liver cell necrosis and severe liver dysfunction caused by alcohol, poisons, drugs and viruses. It develops into hepatic encephalopathy in a short period of time, and the mortality rate is very high. In acute liver failure, endoplasmic reticulum stress-induced apoptosis plays an important role. Acute liver failure leads to apoptosis and necrosis of a large number of liver cells. Endoplasmic reticulum stress is the key to apoptosis. In a mouse model of liver failure, kaempferol can improve liver function and pathological changes in mice, and can inhibit endoplasmic reticulum stress-induced apoptosis of human liver cell line 7702 cells, kaempferol may be through inhibiting endoplasmic reticulum stress The expression of specific apoptotic protein CHOP inhibits endoplasmic reticulum stress to protect liver cells. It can be seen that the application of kaempferol may provide new intervention measures for acute liver injury.
Treat Osteoporosis
Osteoporosis is a serious and painful problem for older people. The researchers did experiments with ovariectomized rats. According to the test results, kaempferol can significantly increase the bone density of ovariectomized rats, and can significantly inhibit the loss of bone calcium and phosphorus in rat urine. According to micro-CT The results show that kaempferol can significantly improve the morphological structure of bone trabeculae in osteoporotic rats. According to the above conclusions, kaempferol can treat osteoporosis.

 With people's understanding of flavonoids, many researchers have successively extracted flavonoids from different plants, including kaempferol. Kaempferol can not only prevent and fight cancer, but also treat diabetes and osteoporosis, protect damaged cells, etc. Some scholars believe that the mechanism of action of kaempferol is likely to be the role of its metabolites in the body. Kaempferol has so many functions, and it is believed that there are still many functions that have not been discovered so far.

 Kaempferol has a variety of functions, and it is generally added as a functional substance in medicine. Few companies or researchers use it in food. Good choice.

Company Introduction-Hunan World Well-being Co.,ltd
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